Mandel Vision Blog: Eyes on a Clearer World

The History of Laser Vision Correction Blog Series ~ Part Two

Keratomileusis and the Excimer Laser

Part 2 of a 4-Part Series

Although Radial Keratotomy was the more widely practiced refractive procedure in the United States, it was not the first.  This accolade is instead reserved for keratomileusis.  In keratomileusis, part of the cornea is removed and then the cornea is reshaped using a blade in order to correct refractive errors.

The process of keratomileusis was first developed in the 1950s, by a Spanish born ophthalmologist named Jose Ignacio Barraquer, M.D.[i] who later moved to Columbia.      

As with R.K., keratomileusis was stumbled upon, as an incidental finding, when Dr. Barraquer performed a corneal transplant on a patient with keratoconus.  Keratoconus is a degenerative corneal disease which is characterized by thinning and cone-shaped protrusion of the central cornea.  Therefore, keratoconus-afflicted corneas are typically steep centrally.  Since healthy corneal tissue is flatter, the corneal transplant flattened the cornea, which caused a reduction in myopia, or nearsightedness.  Subsequent to this finding, Dr. Barraquer spent many years  experimenting with different surgical techniques for the correction of myopia.  He held his first course in Refractive Keratoplasty at the Barraquer Institute in Columbia in 1977.   Seventeen of these courses were held at the institute until 1984.[ii]

 

In 1981, in the U.S., the physicist Rangaswamy Srinivasan discovered that the ultraviolet-light-based excimer laser could be applied in etching or drilling organic solids, including human tissue, without causing thermal damage to the surrounding area.[iii]  In 1983, he began collaborating with ophthalmic surgeon Stephen Trokel, M.D.  Together they developed the excimer laser used in refractive surgery today.  This is a cold ultraviolet laser used to reshape the cornea.  The laser uses UV light to remove microscopic amounts of corneal tissue.  Its precision is at the level of a micron. 

 

In 1985, Dr. Mandel was part of the first team, along with Dr. Trokel, proving that the excimer laser was effective in refractive surgery.  Based on Dr Mandel’s work, he won the WIlliam Warner Hoppin Award from the New York Academy of Science and was recruited to Harvard’s Laser Laboratory to work on the next generation of research:  large area ablation (PRK).  Dr. Mandel's work, which was the first paper proving that the excimer laser works in current laser vision correction techniques, was presented in 1987 at the leading ophthalmologic research association (ARVO). 

 

The first refractive procedure performed with the excimer laser was PRK (Photo-Refractive Keratomileusis), which was approved by the FDA in 1996 to treat nearsightedness[iv].  FDA approval for farsightedness and astigmatism soon followed. 

In the PRK procedure, the epithelium is gently removed using a specialized epithelial brush.  The cornea beneath is then reshaped using the excimer laser.  A bandage soft contact lens is placed on the eye to allow the epithelium of the cornea to regenerate, which typically takes 72 hours.  Although vision is functional and patients usually go back to work the next day, vision is slightly blurry and the visual recovery period for PRK is generally 7 to 10 days.  Optimal vision then slowly returns over the next several months.

PRK is one of the technologies still utilized today for some patients who are not candidates for LASIK.  These patients include those with both thin corneas and high levels of nearsightedness.  The end results of PRK are just as good as LASIK.  Thus, the determining factor for patients who are candidates for both procedures is convenience.  In our world of immediate gratification, LASIK is the winner as optimal vision is achieved the morning after the procedure. 

Next in this blog series:  Bladed-LASIK Utilizing a Microkeratome

 

The History of Laser Vision Correction Blog Series ~ Part One

Radial Keratotomy

The First Blog in a 4-Part Series

Ever wonder about the origins of Laser Vision Correction?  It’s actually a fascinating story, particularly because it was stumbled upon completely by accident.  In the 1970’s, a Russian Ophthalmologist, Svyatoslav Fyodorov, removed glass splinters from the eye of a patient involved in an accident.[i]  Prior to the accident, the patient was nearsighted and required glasses for distance vision.  After the glass splinters were removed, the patient’s vision actually improved.  That was the impetus for the development of the first refractive surgery procedure by Dr. Fyodorov, known as Radial Keratotomy (R.K.).  R.K. was one of the very first refractive procedures.

To understand how this works, let’s review the functional anatomy of a normal sighted eye in comparison to a nearsighted (myopic) eye.   In a normal sighted eye, light rays from an object come into focus directly on the retina.

A nearsighted (myopic) eye, however is anatomically longer than a normal sighted eye.  Therefore, instead of light rays coming into focus directly on the retina, they come into focus in front of the retina, which creates a blurry image.

This condition can be improved by putting a concave lens in front of the eye with either eyeglasses or contact lenses.  A concave lens is thinner in the middle and thicker around the edges and therefore, light rays that pass through this lens are refracted (bent) in a convergent manner which brings them into focus on the retina.

In order to accomplish this same effect with refractive procedures, since it’s not possible to shorten the eye, the cornea is flattened.  In doing this, the light rays from an image have a shorter distance to travel, and can therefore come into focus directly on the retina, without the need for a corrective lens.  In R.K., a diamond surgical blade, which could be calibrated to different corneal depths, was used to create radial incisions which flattened the cornea to correct nearsightedness (myopia).  These incisions are likened to spokes on a bicycle tire.  

Following the accidental finding, Dr. Fyodorov performed many R.K. procedures. From the post operative results of these procedures, he was able to fine tune the R.K. procedure and later predict the number of incisions required to correct different amounts of nearsightedness.  Dr. Fyodorov's data then served as a template for other refractive surgeons. R.K. is one of the earliest, and most widely practiced, refractive techniques from which our current laser vision correction technology evolved.  Both LASIK and PRK laser vision correction performed today employ the same concept as the original R.K. procedure:  changing the shape of the cornea to correct different refractive errors.  The advancement in technology over the years has improved the safety and efficacy of laser vision correction.  It has also enabled refractive surgeons to correct not only nearsightedness (as with R.K.), but farsightedness (hyperopia), astigmatism and presbyopia (the need for reading glasses over age 40), as well. 

Next in this blog series:  Keratomileusis and the Excimer Laser

 

Monovision Laser Vision Correction: An Alternative to Reading Glasses

One of the most common questions we hear from prospective patients over the age of 40 is: “Am I a candidate for LASIK or PRK laser vision correction if I only need reading glasses?” The answer may surprise you: It's yes! The common misconception is that laser vision correction is only for patients who are lifelong glasses or contact lens wearers. However, with the advantage of the monovision approach, patients who only wear reading glasses can also benefit from the procedure. Even better news: For those patients who truly have 20/20 distance vision in each eye without corrective lenses, the laser vision correction procedure is half the price, since only one eye is corrected.

Monovision is a tried and true approach to avoiding or minimizing the need for reading or computer glasses, and is a laser vision correction procedure in which one eye is optimized for distance vision and the other for near vision tasks. With monovision correction, although both eyes are still working together, one eye is relied upon much more for distance, while the other eye is relied upon for near, which is why it’s called monovision (from the term monocular, meaning one eye). Your brain has neuroplasticity, so you can train your brain to automatically, and seamlessly, switch between the eyes as you change your focus from near to distant objects, and vice versa. Monovision is also commonly used as a customized option in LASIK and PRK laser vision correction procedures for those patients who are either nearsighted or farsighted and over the age of 40 who have lost their ability to see clearly up close.

In order to understand monovision, you need to understand how the visual system works, as well as some key ophthalmic terms. When a patient reaches their mid 40’s and loses the ability to accommodate, (or adjust their focusing power for near vision) they need bifocals or reading glasses. This condition is called presbyopia, and the lenses used to correct this condition are plus powered lenses which enable the patient to see clearly for near vision tasks. In a normal sighted eye, light rays from distant objects are focused directly on the retina to produce a clear image without the need for corrective lenses. In a nearsighted (myopic) eye, the eye is anatomically longer than that of a normal sighted eye. Therefore, light rays from distant objects come into focus before they reach the retina. This condition results in an eye that cannot see clearly in the distance, but can see clearly up close (without the help of corrective lenses). This is the concept that is employed in monovision correction.

All patients have a dominant eye, which is the eye that is preferred for visual tasks. In the monovision approach, the non-dominant eye is purposely made slightly nearsighted to optimize reading vision. This means that vision in that eye will be clearer up close for near vision tasks, but blurry when viewing distant objects. The degree of correction chosen for reading correction will be customized for each patient’s visual needs. The factors considered in choosing the amount of correction for reading vision include the refractive error (prescription) of the eye, the patients’ age, profession and hobbies. The goal for the dominant eye is for it to see clearly in the distance. If a patient is nearsighted or farsighted, the dominant eye also requires laser vision correction treatment to correct that eye for distance vision. If a patient has a normal sighted dominant eye, that eye does not require treatment, so only the non-dominant eye is corrected for near vision.

Is it possible to train yourself to adjust to this different type of vision? YES. Monovision takes advantage of brain plasticity to help you learn to automatically see both near and far objects. How motivated you are to adapt to this customized vision and take advantage of your brains plasticity, is the best predictor of success with monovision.

Not everyone is an optimal candidate for this type of laser vision correction procedure. Therefore, a consultation, including a thorough medical eye exam, is necessary to determine whether monovision is the right choice for you. This type of correction can also be simulated with a contact lens so that patients can see what monovision is like prior to having this procedure. Monovision correction can also be achieved with contact lenses, but is usually not successful in eyeglasses.

There is a slight compromise with monovision, as two eyes working together typically give you better vision than one eye working alone. There is also a learning curve to adapt to monovision. However, after an adjustment period, the motivation to avoid bifocals or reading glasses is usually strong enough to overcome this. Depth perception can be affected slightly, but usually not enough to affect daily activities. At Mandel Vision, we do recommend driving glasses until you comfortably adapt to monovision. Once the brain adjusts to monovision, most patients are very happy with their customized procedure. Moreover, they are ecstatic that they no longer have to reach for their reading glasses every time they attempt to read a restaurant menu!

Click here to learn more about LASIK and PRK laser vision correction at Mandel Vision.

Call Mandel Vision® today, at 888-866-3681, for your free laser vision correction evaluation, with corneal surgeon, Eric R. Mandel, M.D., to see if you qualify for this exciting alternative to reading glasses.